Product Description
MOTS-c (12S rRNA c-type mitochondrial open reading frame) is a naturally occurring 16-amino acid mitochondrial-derived peptide and a crucial regulator of systemic metabolic homeostasis. Unlike nuclear-encoded hormones, it is encoded by the mitochondrial genome and translocates to the nucleus during metabolic stress responses. It acts directly on skeletal muscle and adipose tissue, regulating carbohydrate and lipid metabolism pathways, optimizing energy expenditure, and enhancing cellular resilience. In biochemical research, it is a powerful tool for studying longevity, mitochondrial signaling, and metabolic adaptation.
Product Advantages
MOTS-c proponents in metabolism and longevity research utilize its unique signaling pathways to study enhanced physical endurance, energy utilization, and insulin sensitivity. Since endogenous MOTS-c levels decline with age, supplementation with this peptide can directly support metabolic flexibility and promote cellular repair under impaired environmental stress.
Metabolic Flexibility Support: It activates the AMPK signaling pathway, promotes glucose uptake in skeletal muscle, and promotes fatty acid oxidation, thereby optimizing metabolic energy expenditure.
Enhanced physical endurance: Laboratory evaluations show that it significantly improves mitochondrial biosynthesis and respiration, thereby enhancing overall energy output, athletic performance, and muscle resilience.
Anti-aging and cellular longevity: MOTS-c plays a key regulatory role by combating systemic insulin resistance and age-related metabolic decline, protecting cellular networks from age-related degeneration.